- Food Ingredient[11]
- Amino Acid[5]
- pharmaceutical[3]
- plant extract[2]
- sweetener[2]
- Organic Intermediate[1]
- Pharmaceutical[1]
- Polymer[1]
Supply Topiramate/CAS: 97240-79-4
Product Detailed
Topiramate
1. CAS RN: 97240-79-4
2. Structural Formula:
3. Molecular formula & Molecular weight: C12H21NO8S 339.37
4. Appearance: It's a white to off-white powder. Freely soluble in dichloromethane
5. Quality Standard: USP32, purity ≥ 98.0%
6. Usage: It's a new drug of anticonvulsants.
7. Storage: It stored in sealed containers, cool and dry place, and away from light.
8. Packing: Paper bucket, 25kg/package.
9. HS CODE: 2932 9990.90
Topiramate is a white crystalline powder. It is a derivative of the naturally-occurring monosaccharide D-fructose. It is freely soluble in acetone, chloroform, dimethylsulphoxide, and ethanol. The solubility of topiramate in water is 9.8mg/ml.
Topiramate is an anti-epileptic drug
| Items of Analysis | Test Results | Results |
| Appearance | White to off-white powder. | Complies |
| Identification | Infrared Absorption | Complies |
| The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay | Complies | |
| Specific rotation | Between -28.6°and -35.0°,measured at 20° | -32.50° |
| Water | ≤0.5% | 0.19% |
| Residue on ignition | ≤0.1% | 0.06% |
| Heavy metals | ≤10ppm | Complies |
| Related compounds by HPLC | Fructose not more than 0.3% | Fructose 0.06% |
| Compound A not more than 0.3% | Compound A 0.06% | |
| Other individual impurity not more than 0.1% | Individual impurity 0% | |
| Total impurities not more than 0.5% | Total impurities 0.14% | |
| Limit of sulfamate and sulfate | Sulfamate ion not more than 0.10% | Complies |
| Sulfate ion not more than 0.10% | Complies | |
| Assay | Topiramate contains not less than 98.0% and not more than the equivalent of 102.0% of C12H21NO8S, calculated with reference to the Anhydrous Basis. | 99.4% |
| Conclusion | The material complies with respect to USP33 | |
